DiaCarta Technology Platforms

Single · Multiplex · Sequencing

We use our two core technologies, XNA technology and SuperbDNA™ technology, on three different technology platforms, single gene or small gene panel platform, multiplex assays for multiple gene targets, and high-throughput targeted and non-targeted NGS analysis.

Single Gene or Small Gene Panel Platform

The single gene or small gene panel mutation detection uses qPCR technique powered by XNA technology to confirm the targeted gene mutations in less than 4 hours. The assay is simple, straightforward and have been validated in commonly used qPCR instruments from well-known vendors. Although these tests do not directly give information about the nature of the mutation, the researchers can obtain the exact mutations by sequencing of regular PCR products powered by XNA Technology.

The single target gene expression level measurement and genotyping, or target DNA amounts can be achieved in 96-well plate assay by pre-coating the target capturing probes on the bottom of the well and detect target DNA biomarker or gene expression using SuperbDNA™ technology.

Featured products and research lab services are shown below.

Single Gene Mutation Detection

Colon Cancer Mutation Detection

Radiation Toxicity Measurement

HPV mRNA Screening

Multiplex Assays for Multiple Gene Targets

Multiple assays apply for multiple gene targets when a qPCR instrument or a single plate assay will not meet the needs due to the limitation of the target gene numbers. In these multiple assays, discs or beads that are barcoded can track multiple targets and quantify the amounts of the targets in a single sample, either using XNA technology or SuperbDNA™ technology. The method is partially automated to meet the mid to high throughput needs.

Featured products and research lab services (in Multiplex Assay format) are shown below.

Single Gene Mutation Detection

Colon Cancer Mutation Detection

Radiation Toxicity Measurement

HPV mRNA Screening

High-Throughput Targeted and Non-Targeted NGS Analysis

For a large number of gene targets that need detailed sequence information, targeted NGS sequencing is a powerful tool when combined with XNA technology. The use of XNA technology in targeted NGS gene panel allows reduction of sequencing depth by 30x without losing mutation information, saving runtime, analysis, and the ultimate cost.

Featured services are shown below.

OptiSeq™ Target Gene Sequencing (CLIA LAB and research services)

NGS Sequencing Services
(Research only)

Overview and Comparison of the Three Technology Platforms

Need Help?

Call us: +1 (800) 878-6662

Email us: information@diacarta.com

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