Scientist/Senior Scientist, NGS Assay Development

Richmond, CA
Posted 4 months ago

DiaCarta is seeking a highly motivated, experienced and interactive Scientist/Senior Scientist NGS Assay Development to lead one of the key areas in R&D. The new team leader will initiate, direct and execute pre-clinical scientific research and NGS product development activities. The activities will be focused on developing and launching new NGS tests for IVD cancer diagnostics applications. The successful candidate will have outstanding attention to detail, enjoy working in a fast-paced multidisciplinary team environment, and have exceptional hands on laboratory skills. The successful candidate should be able to apply a wide variety of scientific principles and concepts to assay design, assay development and troubleshooting. This is a full-time role in Richmond and you will be reporting to the R&D VP.

Key Responsibilities

  • Contributes very substantially and intellectually to research and development
  • Develops new molecular biology assays and optimizes existing assays
  • Leads projects to create and develop novel nucleic acid based diagnostic tests; including planning, feasibility testing, protocol development, optimization, verification, validation, and launch
  • Responsible for projects and associated timelines and deliverable
  • Thoroughly comprehends the objectives and vision of the work
  • Independently generates, develops and advances new ideas
  • Independently designs and executes moderately to high complexity experiments
  • Performs basic NGS data analysis
  • May manage Research Associates
  • Documents research progress under a Quality Management System
  • Interacts with on-site CLIA lab, R&D groups, product management, commercial and external collaborators
  • Communicates progress directly with colleagues and senior management

Qualifications

  • PhD in molecular biology or closely related field, or equivalent experience
  • 2-5 years of industry experience.
  • Liquid biopsy cancer diagnostics and NGS experience are a must
  • Experience in IVD assay development is preferred

Knowledge, Skills and Abilities

  • Track record of originating, developing novel nucleic acid techniques and assays
  • Proven success in managing collaborative and individual projects, previous experience managing research associates a plus
  • Able to provide a basic level of leadership to Scientists and junior staff
  • Demonstrated success in applying independent scientific judgment in experimental design and analysis
  • Experience with nucleic acid technologies relating to NGS, qPCR, multiplex PCR, digital PCR, and microarrays
  • Expert in cfDNA, DNA/RNA isolation and purification, primers design, assay development and optimization
  • Very strong analytical and problem-solving skills
  • Adept with Excel and basic statistical analysis
  • Bioinformatics skills such as programming (e.g. PERL, python) and data mining are a plus
  • Skilled at writing clear plans, reports and SOPs
  • Experience with Design Control is a plus

Physical Demands and Work Environment

  • Duties are typically performed in laboratory settings (at least 70% of the time)
  • Standing or sitting for long periods of time may be necessary
  • Duties may require working outside normal working hours (evenings and weekends) at times

Job Type

  • Full-Time

Job Features

Job CategoryR&D

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